The impossible has happened! DOCTOR DOOM has taken over the world! And the Fantastic Four are NOT going to let that stand. As Reed locks himself in his lab, trying to solve the Problem of Doom, Ben treats Sue to a trip to NYC with their mutual friend, JEN "SHE-HULK" WALTERS, to help get her mind off of things. But tensions after vampires overran the world in their Blood Hunt remain, and when Ben, Sue and Jen find themselves on the wrong side of mob justice, they face a choice...and it's one they will not be able to take back!